Mitochondrial dysfunction in uremic cardiomyopathy
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction in uremic cardiomyopathy.
Uremic cardiomyopathy (UCM) is characterized by metabolic remodelling, compromised energetics, and loss of insulin-mediated cardioprotection, which result in unsustainable adaptations and heart failure. However, the role of mitochondria and the susceptibility of mitochondrial permeability transition pore (mPTP) formation in ischemia-reperfusion injury (IRI) in UCM are unknown. Using a rat model...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2015
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00442.2014